Home Security Hair Loss and Disruptive Tech: Can Stem Cell Treatments Deliver?

Hair Loss and Disruptive Tech: Can Stem Cell Treatments Deliver?

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It’s common for a person to notice signs of hair loss as they age. However, for many people, losing their hair is akin to losing a part of their identity. Hair loss is a widespread problem that plagues both men and women globally. As such, there is a strong demand to introduce effective methods to combat hair loss, leading to new and sometimes outlandish methods to cure baldness. Here’s what you need to know about how technology could help you keep your luscious locks longer.

Stem Cell Hair Regrowth Study

Did you know that hair is the fastest-growing tissue in the body? Every day, the average person experiences 0.3 to 0.4 mm of hair growth. Even more interesting is the fact that all of your hair follicles are present from your birth stages. No new follicle will grow throughout your lifespan. Consequently, people are now seeking ways to care for their precious follicles at earlier ages to prevent and hopefully cure baldness.

Pelage Pharmaceuticals recently introduced a new method of stimulating hair follicles that has serious potential to upend the market. The company’s non-invasive stem cell hair regrowth procedure leverages the regenerative capabilities provided by stem cells to reactivate and heal follicles at their core.

The topical small molecule drug platform can specifically target follicles that require stimulation. The stem cells integrate into the follicle, causing it to reactivate from a dormant state. The procedure focuses on Hair Follicle Stem Cells (HFSCs)  and how to turn their biological switch on and off.

Notably, this study included researchers from UCLA. The team successfully demonstrated the reactivation of hair follicles using this method. This demonstration was part of a larger campaign to secure funding to expand research. The team managed to acquire $16.75M in Series A Financing led by institutional investors Google Ventures.

Benefits of HFSC Research

There are many benefits to this style of hair regrowth. For one, the process is nonevasive. Unlike older methods like hair transplants, the patient doesn’t have to undergo any procedure. As such, this approach lowers costs, reduces risks, and helps to alleviate congestion In medical facilities.

Pelage Pharmaceuticals

Pelage Pharmaceuticals entered the market in 2018 and is based in Los Angeles, California. The company’s latest hair follicle repair is PP405. This topical ointment uses a small molecule structure to reactivate hair follicles directly. Notably, PP405 is currently undergoing phase clinical trials but has already seen significant support from investors. Pelage Pharmaceuticals raised a total of $30.8M from two funding rounds and is privately owned.

Hair Loss Statistics that You Should Know

New statistics reveal some troubling trends, including the fact that hair loss is on the rise. According to a recent study, the average person will shed around 100 strands of hair daily. This shedding will occur from various regions of the scalp when a person is healthy. However, when the shedding comes from a single spot, it’s usually a sign of underlying health issues or the onset of Androgenetic Alopecia, also known as male pattern baldness.

Hair loss affects men more than women. Specifically, studies revealed that around 65% of American men will experience hair loss by 35. The same statistics show that 85% of men and 33% of women will encounter hair loss in their lives. When broken down by demographics, 25% of men aged 30 will already show signs of hair loss.

Source – Pelage Pharmaceuticals

These numbers increase with age. By the time you are 50, 50% of males will have some form of balding occurring. Additional studies revealed that 50% of women in menopause will deal with hair loss issues. These statistics correlate with other studies that have shown that hair loss in 20-year-olds is at an all-time high.

Causes of Hair Loss

There are several reasons that people experience baldness or excessive hair loss in their lives. The most common is genetics. Male pattern baldness can be passed down from your parents. If your dad is bald, the chances are high that you will have the same haircut at their age.

Androgenic Alopecia

Androgenic Alopecia is an autoimmune disease that affects millions of people globally. This condition can be brought on by a genetic predisposition and hormonal scenarios. Notably, Androgenic Alopecia can lead to patches of hair falling out across the body. As such, if you experience hair loss on your face, chest, armpits, or other areas, in addition to your scalp, it’s likely to be Androgenic Alopecia.

Diets

Another factor that has been found to influence baldness is your diet. Your body needs certain proteins and vitamins to build healthy hair and maintain follicle health. When nutrients like iron, zinc, and proteins are missing, your body can’t create or maintain follicle health resulting in hair loss.

Studies have shown that eating fruits, vegetables, and whole grains contributes to follicle health. Reversely, eating items like certain fish that have high mercury concentrations can lead to hair loss. Also, losing a lot of weight quickly or through surgery has been shown to reduce follicle health.

Environmental Pollution

The world’s pollution problem continues to affect people’s health in negative ways. Those who live in high-pollution areas are more likely to experience hair loss. Low-quality air and water are two main factors that have been linked to reduced follicle health, resulting in hair loss.

Lifestyles

Another leading factor that will determine the health of your hair is the lifestyle you choose. Choosing a healthy and happy lifestyle will be the best way to keep your locks flowing. Studies have shown that stress, depression, lack of sleep, and drug use can all lead to increased hair follicle damage.

Smoking and drinking excessively are other conditions that can lead to lowered immune deficiency, resulting in alopecia hair loss. These activities can stress the body and when coupled with a non-active lifestyle, it can result in a person becoming 11x more likely to lose their hair versus someone living a more relaxing life.

Illness

Another leading cause of hair loss is illness. Certain conditions can cause your hair to fall out. In many instances, this type of hair loss will occur in less common areas like the side of the head or on the face. If you notice weird hair loss on your body, it’s time to get a checkup. It could be an autoimmune disorder or nutrient deficiency that your body is attempting to let you know about.

Effects of Hair Loss

The effects of hair loss have been felt throughout history. You can see many efforts to make balding more acceptable throughout history. From the Chinese shaving the center part of their head and folding the back hair over, to the English dawning elaborate wigs, man has sought out ways to deal with the physical and psychological effects of losing their hair.

Hair Loss is a Psychological Condition

One thing that those who haven’t experienced hair loss might not understand is that it’s a physiological condition as well. Losing your hair will affect your self-esteem and can result in social awkwardness and a desire for solitude. Studies show that 43% of men experiencing hair loss feel like they will become less attractive and find it harder to find suitable partners.

Existing Hair Loss Regeneration Strategies

The desire to cure baldness has been shared by mankind for centuries. From preventive shampoo to witchcraft, there is no shortage of originality or innovation when it comes to the desire to cure baldness. Here are a few of the most common ways people deal with baldness today.

Scalp Massages

Scalp massages can stimulate the blood vessels in your scalp. This action can help to bring oxygen and nutrients to your damaged hair follicles. Scalp massagers built specifically to stimulate the follicles are available. These devices have gotten mixed results with many believing they take too long and don’t do enough. However, as a preventive measure, scalp massages are a great idea.

Diet Changes

Anyone serious about slowing hair loss needs to consider changing their diet. Your diet is one of the most important factors determining the health of your hair follicles. Avoid fatty and greasy foods. Instead, go with some healthy options like vegetables and give your hair a fighting chance. Diet changes should be among the first steps you take to prevent or stem hair loss.

Vitamins and Supplements

Adding vitamins and supplements to your day is another great way to ensure your follicles have the nutrition they need to produce healthy strong hair stands. A one-a-day daily vitamin is a great addition to your lifestyle. It ensures that your hair gets the nutrients it needs, even on days you eat unhealthy.

Scalp Care

There are several companies that offer scalp care products. These creams and lotions are designed to stimulate the scalp and follicles, causing them to become active and produce hair. This method of combating baldness is not as effective as using prescription shampoos and ointments.

The scalp care sector continues to expand with options, many unproven or tested. As such, you need to be a bit more cautious to avoid becoming a guinea pig or scammed by someone looking to try their experimental hair cream.

Prescription and OTC Medications

Currently, one of the most effective ways to combat hair loss is through medications. Drugs like Finasteride and minoxidil – each of which comes in different forms (e.g., foams, pills) – have all shown promising results. Notably, Finasteride is the most common drug used to treat hair loss. Sadly, in the United States, there are only two FDA-approved medicated-approve hair loss drugs to treat Alopecia currently, Propecia and Rogaine (Minoxidil).

Hair Transplant to Cure Baldness

A hair transplant is a procedure in which a medical professional removes hair from one part of your body and places it on your scalp. In many instances, the follicles are moved from more active parts of the head to bald areas. The two most commonly used methods of hair transplant are Follicular Unit Extraction (FUE) and Follicular Unit Transplantation (FUT).

Hair transplants are expensive and require you to undergo a surgical procedure. This procedure requires a professional to graft your hair from one part of your head to another. Anytime you have any type of invasive surgery,  risks, costs, and recovery times increase.

Laser Tech to Cure Baldness

High-tech hair loss options continue to spring up in the market. Lasers are one such solution. This method uses beams of light to excite the blood around the follicles. The added circulation works like the massage method, stimulating the area to draw more oxygen and nutrients to the follicle, providing it with the necessary building blocks to heal and grow.

The Capillus82 Mobile Laser Therapy Cap is one of the most popular options in this market. This device uses 32 low-level lasers to stimulate follicles. To operate the device, the user must wear a special laser helmet for 6 minutes daily. Notably, the results from laser therapy vary with some patients saying they experienced regrowth while others stating it was not effective at all.

Is Hair Loss Tech Relatable?

The drive to cure one of humanity’s oldest problems has led to some unique and often weird solutions. In many instances, people just aren’t able to relate to the method or procedures required. For example, you may not be comfortable wearing a laser headset, sitting under pitched soundwaves, or other outlandish methods proposed over the years.

Researchers have long sought out a balance between practicality and effectiveness when dealing with baldness issues. Recently, a lot of attention has been placed on making the tech less noticeable and easier to use. As such, a new wave of hair-saving tech is on the horizon.

To Cure Baldness it will Take Science.

Regardless of whether you’re reading this running your hands through your long curls or scratching your bald head, it’s evident that technology will play a vital role in curing baldness moving forward. In the future, you will see companies like Pelage Pharmaceuticals introduce new and novel methods to stem hair loss. The main thing to understand is that whatever company can provide a reliable and low-cost cure, is sure to reap massive benefits.

Learn about other cool BioTech Now.



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